Your full-service clinical Contract Research Organization (CRO)

One-stop shop

Our integrated approach to your product development programme ensures efficient translation from the in-vitro and preclinical stages through to Proof of Concept.

An all In-house approach

By virtue of Eurofins’ worldwide network of laboratories and dedicated GxP Pharma sites, underpinned by its robust QA programme, we are in an unrivalled position to undertake internally the entire spectrum of activities required to direct and support clinical trials. This allows us to optimize the time and cost of your clinical development projects.

Over three decades dedicated to clinical trials

Our team

A human-scale team with global reach

The Eurofins Optimed team of clinical trial experts is also your point of access to Eurofins’ Biopharma division, a first-class biopharmaceutical outsourcing services organization (Contract Research Organization – CRO and Contract Development & Manufacturing Organization - CDMO), offering a holistic approach to cover the entire chain of compound development in order to maximize your chances to succeed in the clinical stages.

Our clinical trial solutions

We know how much is at stake for sponsors, patients, physicians, and regulators.

Identifying a customizable model that matches the specific needs and strategy of your trial is a long and complex process.

Our flexible and adaptive approach allows you to work simultaneously with any other service provider of your choice, while ensuring optimal cross-company synergy and full control of your project.

 

One-stop shop or pick and mix services.

Whether you are the Head of Clinical Operations of a big Pharmaceutical or Medical Device multinational company, or the founder of a small biotechnology start-up, your needs for external support may vary significantly.

Because your project is unique and requires an individual approach, we provide a comprehensive range of bespoke and adaptable solutions on a stand-alone or full-service package basis.

Our services

Eurofins’ Clinical Trials Unit (CTU)

Protocol Development and trial design

Regulatory Affairs

Medical writing

Global Trial and Site Management

Biometry

Bioanalysis

IMP Development and Manufacturing

Therapeutic Areas

Over 1000 state-of-the-art trials

 

Over the past thirty years, we have gained extensive experience in Early Clinical Development across all therapeutic areas, from conventional FIH (First-into-Human) and phase I trials at our clinical trials unit, through to highly complex, specialized international multi-centre studies in the most challenging indications.

 

Types of trials

 

  • Entry into man
  • Entry into patients
  • Proof of Concept (POC)
  • PK/PD
  • TQT (ICH E14)
  • Absolute, Relative Bioavailability
  • Bioequivalence
  • Drug-Drug Interactions
  • Proportionality
  • Metabolism
  • Food / Gender /Age effect
  • Tobacco
  • Vaccines
  • Muscle Biopsy
  • Micro-dosing
  • Glucose Clamp
  • Sleep Evaluation
  • Biomarkers

Quality Assurance – Delivering Excellence in Early Clinical Development

A Robust, Agile and Purpose-Built Quality Management System

Our Quality Management System (QMS) has been designed to support the specific challenges of Phase I and Phase II trials.

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It is built upon:

  • International regulations and guidelines (ICH-GCP, EMA, FDA, GDPR)
  • A harmonized and controlled documentation framework
  • Strong operational procedures refined through extensive field experience
  • A risk-based, forward-looking approach to quality and compliance

This model allows us to combine the discipline of a global organization with the agility of a specialized early-phase clinical center.

Audits That Drive Performance

Our Quality Assurance team coordinates and executes:

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  • Comprehensive internal audits (processes, TMF, pharmacy, laboratory, IT, safety, operations…)
  • Qualification and oversight of critical vendors (data management, statistics, pharmacovigilance, bioanalysis, computerized systems…)
  • Inspection readiness and support during regulatory inspections (ANSM, EMA, FDA…)
  • Sponsor audits with consistently high satisfaction

Each audit is approached as a value-creation opportunity: we identify risks, anticipate issues, guide continuous improvement, and secure the long-term integrity of your project.

Deviation Management, CAPA and Continuous Improvement

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We apply a rigorous methodology to ensure full traceability and efficient resolution of quality events:

  • Structured identification and documentation of deviations
  • Root-cause analysis using proven tools (5 Why, Ishikawa, risk assessment)
  • Development of corrective and preventive action plans that are relevant, measurable and actionable
  • Verification of effectiveness to guarantee long-lasting improvement
  • Cross-department communication to prevent recurrence

Our goal: a controlled and stable environment that continuously strengthens data integrity and participant safety.

Document Excellence and TMF Mastery

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We operate with a fully structured, audit-ready electronic Trial Master File (eTMF) compliant with EMA and DIA standards.
Our team ensures:

  • TMF completeness and real-time accuracy
  • Consistency of documentation and metadata
  • Proper version control and change traceability
  • End-to-end compliance with EU CTR 536/2014 requirements

This ensures a clean, compliant and inspection-ready TMF at any point in time.

Validated and Secure Computerized Systems

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Our operations rely on a validated digital ecosystem covering EDC, IWRS, pharmacovigilance, bioanalysis, temperature monitoring, eTMF and internal tools.

Based on GAMP5 and GCP principles, our validation framework guarantees:

  • Prospective and lifecycle-based validation of each system
  • Structured change control and documentation
  • Logical and physical security, cybersecurity, and backup/restore testing
  • Full data integrity (ALCOA+) from creation to archiving
  • Regular audits of critical IT vendors

We ensure that your data remain accurate, traceable, secured and protected at every stage.

Training, Competency and Quality Culture

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A strong quality system starts with trained and empowered teams.
We have implemented:

  • A comprehensive onboarding program for all new employees
  • Mandatory and recurrent training on GCP, EU CTR, SOPs and internal systems
  • Competency tracking based on real study experience
  • A culture of ownership, transparency and continuous improvement

Every team member becomes an active contributor to quality.

Why Sponsors Trust Us

Because we deliver:

  • Complete visibility and proactive communication
  • Solution-oriented support, not just compliance checks
  • Early-phase expertise with integrated operations
  • Fast, transparent and rigorous quality management
  • Risk anticipation, not risk reaction
  • Quality that secures timelines, cost, and scientific robustness

Our strength lies in protecting your volunteers, your data and your study outcomes.

Quality is our Commitment.

Reliability is our Signature.

We place quality at the center of every process, every decision, and every study we support.
Our goal is to deliver undeniable operational excellence, irreproachable compliance, and a partnership built on trust, expertise and long-term performance.

Contact us

2025-06-04

1 rue des Essarts
38610 Gières - France

+33 (0)4 38 37 27 40

optimed@eurofins.com

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